PGD & PGS

Preimplantation Genetic Diagnosis (PGD)

Preimplantation Genetic Diagnosis (PGD) is a revolutionary procedure that can alter your family’s genetic destiny. This technique significantly increases the likelihood of having a healthy baby for couples at risk for, or living with, genetic disease. PGD is done in conjunction with IVF and allows us to test your embryos for genetic disease prior to achieving a pregnancy. PGD may be a something to consider if:

 

  • You or your partner have a genetic disease
  • You or your partner are carriers of an abnormal disease
  • You or your partner have a chromosome abnormality, such as translocation
  • You already have a child afflicted with a genetic disease

PGD is integrated into the IVF process and requires minimal effort beyond what you will be already doing for your IVF. PGD involves the following steps:

 

  1. Screening for genetic diseases by a genetic counselor
  2. Normal IVF cycle: stimulation, retrieval, fertilization
  3. Embryo biopsy: a single cell will be removed from each viable embryo, and the cell will be tested for genetic diseases in question
  4. After careful review of the genetic results, healthy embryos will be transferred into the uterus.
  5. Excess embryos may be frozen for future use

To learn more about PGD, ask questions about the process, and determine if it may be the right path for you, contact Lenox Hill Human Reproduction. We look forward to helping you on your journey toward parenthood.

Preimplantation Genetic Screening (PGS)

Preimplantation Genetic Screening (PGS) is done in conjunction with IVF to screen eggs for chromosomal abnormalities. Similar to PGD, PGS is used when no known genetic concerns are present. PGS may be right for you if:

 

  • You are 35 years of age or older
  • Have had two or more miscarriages
  • Had more than two unsuccessful IVF cycles
  • Have otherwise unexplained infertility

Chromosomal abnormalities are responsible for a significant amount of early pregnancy losses. Egg quality is considered to be the major factor of reduced implantation rates, and therefore viable pregnancy rates. With PGS, we are able to screen for chromosomal problems like aneuploidy (abnormal number of chromosomes), broken chromosomes, translocation and other chromosomal abnormality. Only healthy embryos that are free of chromosomal abnormalities will be transferred into uterus for conception.

 

PGS is performed in conjunction with IVF. The process is as follows:

 

  1. Screening for genetic diseases by a genetic counselor
  2. Normal IVF cycle: stimulation, retrieval, fertilization, transfer
  3. Embryo biopsy: a single cell will be removed from each viable embryo, and the cell will be tested evaluated
  4. After careful review of the results, healthy embryos will be transferred into the uterus
  5. Excess embryos may be frozen for future use

 

To learn more about PGS, ask questions about the process, and determine if it may be the right path for you, contact Lenox Hill Human Reproduction. We look forward to helping you on your journey toward parenthood.